Rare mutations may have big impact on schizophrenia pathology

Researchers have long searched for genetic influences in schizophrenia, a neurodevelopmental disorder that disrupts brain activity producing hallucinations, delusions, and other cognitive disturbances. However the disease’s genetic mutations have been identified in only a small fraction — fewer than a quarter — of sequenced patients. A new study now shows that ‘somatic’ gene mutations in brain cells could account for some of the disease neuropathology. View original article here Source

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